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Structure paper

Titlealpha-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling.
Journal, issue, pagesNature, Vol. 553, Page 461-466, Year 2018
Publish dateJun 5, 2017 (structure data deposition date)
AuthorsChen, G. / Liu, Y. / Goetz, R. / Fu, L. / Jayaraman, S. / Hu, M.C. / Moe, O.W. / Liang, G. / Li, X. / Mohammadi, M.
External linksNature / PubMed:29342138
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-5w21:
Crystal Structure of a 1:1:1 FGF23-FGFR1c-aKlotho Ternary Complex
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/PROTEIN BINDING / complex / ligand / receptor / co-receptor / HYDROLASE-PROTEIN BINDING complex

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