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TitleStructural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent.
Journal, issue, pagesStructure, Vol. 26, Page 187-198.e4, Year 2018
Publish dateAug 15, 2017 (structure data deposition date)
AuthorsEly, L.K. / Lolicato, M. / David, T. / Lowe, K. / Kim, Y.C. / Samuel, D. / Bessette, P. / Garcia, J.L. / Mikita, T. / Minor, D.L. / Coughlin, S.R.
External linksStructure / PubMed:29336885
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-6aod:
FXIa antibody complex
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-CO:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsBLOOD CLOTTING/IMMUNE SYSTEM / FXIa Antibody FAB / BLOOD CLOTTING / BLOOD CLOTTING-IMMUNE SYSTEM complex

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