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TitleThe Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
Journal, issue, pagesCell Host Microbe, Vol. 23, Page 101-109.e4, Year 2018
Publish dateNov 21, 2017 (structure data deposition date)
AuthorsKing, L.B. / Fusco, M.L. / Flyak, A.I. / Ilinykh, P.A. / Huang, K. / Gunn, B. / Kirchdoerfer, R.N. / Hastie, K.M. / Sangha, A.K. / Meiler, J. ...King, L.B. / Fusco, M.L. / Flyak, A.I. / Ilinykh, P.A. / Huang, K. / Gunn, B. / Kirchdoerfer, R.N. / Hastie, K.M. / Sangha, A.K. / Meiler, J. / Alter, G. / Bukreyev, A. / Crowe, J.E. / Saphire, E.O.
External linksCell Host Microbe / PubMed:29324225
MethodsX-ray diffraction
Resolution3.172 Å
Structure data

PDB-6bp2:
Therapeutic human monoclonal antibody MR191 bound to a marburgvirus glycoprotein
Method: X-RAY DIFFRACTION / Resolution: 3.172 Å

Source
  • marburg marburgvirus
  • homo sapiens (human)
KeywordsVIRAL PROTEIN/immune system / Marburg / Ravn / Glycoprotein / Complex / VIRAL PROTEIN / VIRAL PROTEIN-immune system complex

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