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TitleThe Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism.
Journal, issue, pagesMol. Cell, Vol. 69, Page 75-86.e9, Year 2018
Publish dateSep 14, 2017 (structure data deposition date)
AuthorsShaban, N.M. / Shi, K. / Lauer, K.V. / Carpenter, M.A. / Richards, C.M. / Salamango, D. / Wang, J. / Lopresti, M.W. / Banerjee, S. / Levin-Klein, R. ...Shaban, N.M. / Shi, K. / Lauer, K.V. / Carpenter, M.A. / Richards, C.M. / Salamango, D. / Wang, J. / Lopresti, M.W. / Banerjee, S. / Levin-Klein, R. / Brown, W.L. / Aihara, H. / Harris, R.S.
External linksMol. Cell / PubMed:29290613
MethodsX-ray diffraction
Resolution3.28006215294 - 3.428 Å
Structure data

PDB-6b0b:
Crystal structure of human APOBEC3H
Method: X-RAY DIFFRACTION / Resolution: 3.28006215294 Å

PDB-6bbo:
Crystal structure of human APOBEC3H/RNA complex
Method: X-RAY DIFFRACTION / Resolution: 3.428 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • discosoma sp. (sea anemone)
  • escherichia coli (E. coli)
KeywordsHYDROLASE/RNA / APOBEC / deaminase. / HYDROLASE / HYDROLASE-RNA complex

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