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Structure paper

TitleStructural insights into humanization of anti-tissue factor antibody 10H10.
Journal, issue, pagesMAbs, Vol. 10, Page 269-277, Year 2018
Publish dateMay 30, 2017 (structure data deposition date)
AuthorsTeplyakov, A. / Obmolova, G. / Malia, T.J. / Raghunathan, G. / Martinez, C. / Fransson, J. / Edwards, W. / Connor, J. / Husovsky, M. / Beck, H. ...Teplyakov, A. / Obmolova, G. / Malia, T.J. / Raghunathan, G. / Martinez, C. / Fransson, J. / Edwards, W. / Connor, J. / Husovsky, M. / Beck, H. / Chi, E. / Fenton, S. / Zhou, H. / Almagro, J.C. / Gilliland, G.L.
External linksMAbs / PubMed:29283291
MethodsX-ray diffraction
Resolution1.64 - 2.6 Å
Structure data

PDB-5w05:
ANTI-TISSUE FACTOR ANTIBODY M59, A HUMANIZED VERSION OF 10H10
Method: X-RAY DIFFRACTION / Resolution: 1.64 Å

PDB-5w06:
HUMAN TISSUE FACTOR IN COMPLEX WITH ANTIBODY M1587
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM

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