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-Structure paper
Title | Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma. |
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Journal, issue, pages | J. Med. Chem., Vol. 61, Page 695-710, Year 2018 |
Publish date | Apr 22, 2017 (structure data deposition date) |
Authors | Mazur, M. / Olczak, J. / Olejniczak, S. / Koralewski, R. / Czestkowski, W. / Jedrzejczak, A. / Golab, J. / Dzwonek, K. / Dymek, B. / Sklepkiewicz, P.L. ...Mazur, M. / Olczak, J. / Olejniczak, S. / Koralewski, R. / Czestkowski, W. / Jedrzejczak, A. / Golab, J. / Dzwonek, K. / Dymek, B. / Sklepkiewicz, P.L. / Zagozdzon, A. / Noonan, T. / Mahboubi, K. / Conway, B. / Sheeler, R. / Beckett, P. / Hungerford, W.M. / Podjarny, A. / Mitschler, A. / Cousido-Siah, A. / Fadel, F. / Golebiowski, A. |
External links | J. Med. Chem. / PubMed:29283260 |
Methods | X-ray diffraction |
Resolution | 1.267 - 1.447 Å |
Structure data | PDB-5nr8: PDB-5nra: PDB-5nrf: |
Chemicals | ChemComp-95N: ChemComp-GOL: ChemComp-HOH: ChemComp-95K: ChemComp-95Q: |
Source |
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Keywords | HYDROLASE / chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 7a / chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 7g / chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 7i |