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TitleCrystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor.
Journal, issue, pagesStructure, Vol. 26, Page 153-160.e4, Year 2018
Publish dateJul 17, 2017 (structure data deposition date)
AuthorsHarvey, E.P. / Seo, H.S. / Guerra, R.M. / Bird, G.H. / Dhe-Paganon, S. / Walensky, L.D.
External linksStructure / PubMed:29276033
MethodsX-ray diffraction
Resolution1.69 - 2.38 Å
Structure data

PDB-5whh:
Crystal Structure of Bcl-2-related protein A1 in complex with stapled peptide (AQ7)T(0EH)LRRFGD(MK8)INFRQ(NH2)
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

PDB-5whi:
Crystal Structure of Bcl-2-related protein A1
Method: X-RAY DIFFRACTION / Resolution: 1.69 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CAD:
CACODYLIC ACID

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsAPOPTOSIS / stapled peptide

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