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-Structure paper
Title | In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-beta-lactamase Inhibitors. |
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Journal, issue, pages | J. Med. Chem., Vol. 61, Page 1255-1260, Year 2018 |
Publish date | May 20, 2016 (structure data deposition date) |
![]() | Cain, R. / Brem, J. / Zollman, D. / McDonough, M.A. / Johnson, R.M. / Spencer, J. / Makena, A. / Abboud, M.I. / Cahill, S. / Lee, S.Y. ...Cain, R. / Brem, J. / Zollman, D. / McDonough, M.A. / Johnson, R.M. / Spencer, J. / Makena, A. / Abboud, M.I. / Cahill, S. / Lee, S.Y. / McHugh, P.J. / Schofield, C.J. / Fishwick, C.W.G. |
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Methods | X-ray diffraction |
Resolution | 1.744 Å |
Structure data | ![]() PDB-5k48: |
Chemicals | ![]() ChemComp-S5Z: ![]() ChemComp-FMT: ![]() ChemComp-ZN: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / metallo beta-lactamase / antibiotic resistance / carbapenamase. inhibitor |