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-Structure paper
Title | Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma. |
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Journal, issue, pages | Sci Rep, Vol. 7, Page 17993-17993, Year 2017 |
Publish date | Aug 22, 2017 (structure data deposition date) |
![]() | Drew, A.E. / Moradei, O. / Jacques, S.L. / Rioux, N. / Boriack-Sjodin, A.P. / Allain, C. / Scott, M.P. / Jin, L. / Raimondi, A. / Handler, J.L. ...Drew, A.E. / Moradei, O. / Jacques, S.L. / Rioux, N. / Boriack-Sjodin, A.P. / Allain, C. / Scott, M.P. / Jin, L. / Raimondi, A. / Handler, J.L. / Ott, H.M. / Kruger, R.G. / McCabe, M.T. / Sneeringer, C. / Riera, T. / Shapiro, G. / Waters, N.J. / Mitchell, L.H. / Duncan, K.W. / Moyer, M.P. / Copeland, R.A. / Smith, J. / Chesworth, R. / Ribich, S.A. |
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Methods | X-ray diffraction |
Resolution | 1.92 - 2 Å |
Structure data | ![]() PDB-6arj: ![]() PDB-6arv: |
Chemicals | ![]() ChemComp-SAH: ![]() ChemComp-BW4: ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-HOH: ![]() ChemComp-BW7: |
Source |
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![]() | TRANSFERASE / protein-inhibitor complex / protein arginine methyltransferase |