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Structure paper

TitleA Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
Journal, issue, pagesJ. Cell Biol., Vol. 217, Page 745-762, Year 2018
Publish dateMar 29, 2017 (structure data deposition date)
AuthorsColaluca, I.N. / Basile, A. / Freiburger, L. / D'Uva, V. / Disalvatore, D. / Vecchi, M. / Confalonieri, S. / Tosoni, D. / Cecatiello, V. / Malabarba, M.G. ...Colaluca, I.N. / Basile, A. / Freiburger, L. / D'Uva, V. / Disalvatore, D. / Vecchi, M. / Confalonieri, S. / Tosoni, D. / Cecatiello, V. / Malabarba, M.G. / Yang, C.J. / Kainosho, M. / Sattler, M. / Mapelli, M. / Pece, S. / Di Fiore, P.P.
External linksJ. Cell Biol. / PubMed:29269425
MethodsX-ray diffraction
Resolution2.7 - 3.13 Å
Structure data

PDB-5njj:
PTB domain of human Numb isoform-1
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-5njk:
PTB domain of human Numb isoform-1
Method: X-RAY DIFFRACTION / Resolution: 3.13 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsENDOCYTOSIS / PTB domain / Numb / breast cancer

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