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-Structure paper
Title | Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo. |
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Journal, issue, pages | ACS Med Chem Lett, Vol. 8, Page 1252-1257, Year 2017 |
Publish date | Jul 17, 2017 (structure data deposition date) |
![]() | Kuttruff, C.A. / Ferrara, M. / Bretschneider, T. / Hoerer, S. / Handschuh, S. / Nosse, B. / Romig, H. / Nicklin, P. / Roth, G.J. |
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Methods | X-ray diffraction |
Resolution | 1.66 - 1.82 Å |
Structure data | ![]() PDB-5ohi: ![]() PDB-5olb: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-NA: ![]() ChemComp-K: ![]() ChemComp-P3G: ![]() ChemComp-CL: ![]() ChemComp-9V8: ![]() ChemComp-HOH: ![]() ChemComp-PGE: ![]() ChemComp-SO4: ![]() ChemComp-6ZO: |
Source |
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![]() | HYDROLASE / PHOSPHOLIPASE / HYDROLASE-HYDROLASE INHIBITOR COMPLEX |