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TitleMutations in the U11/U12-65K protein associated with isolated growth hormone deficiency lead to structural destabilization and impaired binding of U12 snRNA.
Journal, issue, pagesRNA, Vol. 24, Page 396-409, Year 2018
Publish dateJun 28, 2017 (structure data deposition date)
AuthorsNorppa, A.J. / Kauppala, T.M. / Heikkinen, H.A. / Verma, B. / Iwai, H. / Frilander, M.J.
External linksRNA / PubMed:29255062
MethodsNMR (solution)
Structure data

PDB-5obn:
NMR solution structure of U11/U12 65K protein's C-terminal RRM domain (381-516)
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsSPLICING / Minor spliceosome / RNA binding

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