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Structure paper

TitleConserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 115, Page 168-173, Year 2018
Publish dateJun 16, 2017 (structure data deposition date)
AuthorsRaymond, D.D. / Bajic, G. / Ferdman, J. / Suphaphiphat, P. / Settembre, E.C. / Moody, M.A. / Schmidt, A.G. / Harrison, S.C.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:29255041
MethodsX-ray diffraction
Resolution1.634 - 2.79 Å
Structure data

PDB-5w6c:
UCA Fab (unbound) from 6649 Lineage
Method: X-RAY DIFFRACTION / Resolution: 1.634 Å

PDB-5w6g:
Human antibody 6649 in complex with influenza hemagglutinin H1 Solomon Islands
Method: X-RAY DIFFRACTION / Resolution: 2.79 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • influenza a virus (a/solomon islands/3/2006(h1n1))
KeywordsIMMUNE SYSTEM / Antibody / FAB / Influenza H1N1 / VIRAL PROTEIN/IMMUNE SYSTEM / VIRAL PROTEIN-IMMUNE SYSTEM complex

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