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-Structure paper
Title | Structures of PPAR gamma complexed with lobeglitazone and pioglitazone reveal key determinants for the recognition of antidiabetic drugs |
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Journal, issue, pages | Sci Rep, Vol. 7, Page 16837-16837, Year 2017 |
Publish date | Jul 26, 2017 (structure data deposition date) |
Authors | Lee, M.A. / Tan, L. / Yang, H. / Im, Y.G. / Im, Y.J. |
External links | Sci Rep / PubMed:29203903 |
Methods | X-ray diffraction |
Resolution | 1.7 - 1.801 Å |
Structure data | PDB-5y2o: PDB-5y2t: |
Chemicals | ChemComp-8N6: ChemComp-HOH: ChemComp-8LX: |
Source |
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Keywords | TRANSCRIPTION / PPARgamma / nuclear receptor / pioglitazone / thiazolidinedione / ligand binding domain |