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TitleConformational switch of the bacterial adhesin FimH in the absence of the regulatory domain: Engineering a minimalistic allosteric system.
Journal, issue, pagesJ. Biol. Chem., Vol. 293, Page 1835-1849, Year 2018
Publish dateNov 9, 2016 (structure data deposition date)
AuthorsRabbani, S. / Fiege, B. / Eris, D. / Silbermann, M. / Jakob, R.P. / Navarra, G. / Maier, T. / Ernst, B.
External linksJ. Biol. Chem. / PubMed:29180452
MethodsX-ray diffraction
Resolution1.604 Å
Structure data

PDB-5mca:
Crystal structure of FimH-LD R60P variant in the apo state
Method: X-RAY DIFFRACTION / Resolution: 1.604 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • escherichia coli k-12 (bacteria)
KeywordsSUGAR BINDING PROTEIN / FimH / type 1 pilus / pilus / UTI / urinary tract infection / bladder / Escherichia coli

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