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TitleA neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells.
Journal, issue, pagesJ. Biol. Chem., Vol. 293, Page 941-952, Year 2018
Publish dateMay 9, 2017 (structure data deposition date)
AuthorsKroh, H.K. / Chandrasekaran, R. / Zhang, Z. / Rosenthal, K. / Woods, R. / Jin, X. / Nyborg, A.C. / Rainey, G.J. / Warrener, P. / Melnyk, R.A. ...Kroh, H.K. / Chandrasekaran, R. / Zhang, Z. / Rosenthal, K. / Woods, R. / Jin, X. / Nyborg, A.C. / Rainey, G.J. / Warrener, P. / Melnyk, R.A. / Spiller, B.W. / Lacy, D.B.
External linksJ. Biol. Chem. / PubMed:29180448
MethodsX-ray diffraction
Resolution2.79 Å
Structure data

PDB-5vqm:
Clostridium difficile TcdB-GTD bound to PA41 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.79 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • peptoclostridium difficile (bacteria)
  • homo sapiens (human)
KeywordsTOXIN/IMMUNE SYSTEM / toxin antibody / TOXIN-IMMUNE SYSTEM complex

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