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TitleBacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity.
Journal, issue, pagesNat Commun, Vol. 8, Page 1601-1601, Year 2017
Publish dateSep 21, 2017 (structure data deposition date)
AuthorsPantophlet, R. / Trattnig, N. / Murrell, S. / Lu, N. / Chau, D. / Rempel, C. / Wilson, I.A. / Kosma, P.
External linksNat Commun / PubMed:29150603
MethodsX-ray diffraction
Resolution2.271 Å
Structure data

PDB-6b3d:
Crystal structure of anti-HIV antibody PGT128 in complex with a bacterially derived synthetic mimetic of Man9.
Method: X-RAY DIFFRACTION / Resolution: 2.271 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / antibody / glycan / mannose

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