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Structure paper

TitleStructural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.
Journal, issue, pagesSci Rep, Vol. 7, Page 15121-15121, Year 2017
Publish dateJun 7, 2017 (structure data deposition date)
AuthorsPark, H.W. / Ma, Z. / Zhu, H. / Jiang, S. / Robinson, R.C. / Endow, S.A.
External linksSci Rep / PubMed:29123223
MethodsX-ray diffraction
Resolution1.85 - 2.79 Å
Structure data

PDB-5w3d:
The structure of kinesin-14 wild-type Ncd-ADP dimer
Method: X-RAY DIFFRACTION / Resolution: 2.79 Å

PDB-5wde:
Crystal structure of the KIFC3 motor domain in complex with ADP
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-5wdh:
Motor domain of human kinesin family member C1
Method: X-RAY DIFFRACTION / Resolution: 2.248 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-UNX:
Unknown entry

ChemComp-HOH:
WATER

Source
  • drosophila melanogaster (fruit fly)
  • homo sapiens (human)
KeywordsMOTOR PROTEIN / NCD / MICROTUBULE / MOTOR / KINESIN / CELL CYCLE / motor domain / adp / STRUCTURAL GENOMICS / STRUCTUR AL GENOMICS CONSORTIUM / SGC / Structural Genomics Consortium

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