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Structure paper

TitleStructural destabilization of tropomyosin induced by the cardiomyopathy-linked mutation R21H.
Journal, issue, pagesProtein Sci., Vol. 27, Page 498-508, Year 2018
Publish dateJun 15, 2016 (structure data deposition date)
AuthorsLy, T. / Krieger, I. / Tolkatchev, D. / Krone, C. / Moural, T. / Samatey, F.A. / Kang, C. / Kostyukova, A.S.
External linksProtein Sci. / PubMed:29105867
MethodsX-ray diffraction
Resolution1.4964 Å
Structure data

PDB-5kht:
Crystal structure of the N-terminal fragment of tropomyosin isoform Tpm1.1 at 1.5 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.4964 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • saccharomyces cerevisiae (brewer's yeast)
Keywordsactin-binding protein / tropomyosin / coiled coil

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