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-Structure paper
Title | Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule. |
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Journal, issue, pages | Sci Rep, Vol. 7, Page 14409-14409, Year 2017 |
Publish date | Feb 15, 2017 (structure data deposition date) |
Authors | Ferrandez, Y. / Zhang, W. / Peurois, F. / Akendengue, L. / Blangy, A. / Zeghouf, M. / Cherfils, J. |
External links | Sci Rep / PubMed:29089502 |
Methods | X-ray diffraction |
Resolution | 2.59 Å |
Structure data | PDB-5n6o: |
Chemicals | ChemComp-GDP: ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | PROTEIN BINDING / Rac / GTPase / GDP / guanine exchange factor / GEF |