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-Structure paper
Title | Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein-Coupled Receptor Kinase 2 Inhibitors. |
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Journal, issue, pages | Mol. Pharmacol., Vol. 92, Page 707-717, Year 2017 |
Publish date | Jul 13, 2017 (structure data deposition date) |
![]() | Bouley, R. / Waldschmidt, H.V. / Cato, M.C. / Cannavo, A. / Song, J. / Cheung, J.Y. / Yao, X.Q. / Koch, W.J. / Larsen, S.D. / Tesmer, J.J.G. |
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Methods | X-ray diffraction |
Resolution | 2.31 - 3.1 Å |
Structure data | ![]() PDB-5wg3: ![]() PDB-5wg4: ![]() PDB-5wg5: |
Chemicals | ![]() ChemComp-AFM: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-AFV: ![]() ChemComp-ZSO: |
Source |
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![]() | Transferase/Signaling Protein / Transferase-Signaling Protein complex / TRANSFERASE / beta-adrenergic receptor kinase 1 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 |