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TitleBlocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression.
Journal, issue, pagesCancer Res., Vol. 77, Page 6950-6962, Year 2017
Publish dateFeb 17, 2017 (structure data deposition date)
AuthorsKim, S. / Alsaidan, O.A. / Goodwin, O. / Li, Q. / Sulejmani, E. / Han, Z. / Bai, A. / Albers, T. / Beharry, Z. / Zheng, Y.G. ...Kim, S. / Alsaidan, O.A. / Goodwin, O. / Li, Q. / Sulejmani, E. / Han, Z. / Bai, A. / Albers, T. / Beharry, Z. / Zheng, Y.G. / Norris, J.S. / Szulc, Z.M. / Bielawska, A. / Lebedyeva, I. / Pegan, S.D. / Cai, H.
External linksCancer Res. / PubMed:29038344
MethodsX-ray diffraction
Resolution2.252 Å
Structure data

PDB-5uut:
N-myristoyltransferase 1 (NMT) bound to myristoyl-CoA
Method: X-RAY DIFFRACTION / Resolution: 2.252 Å

Chemicals

ChemComp-MYA:
TETRADECANOYL-COA

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / myristoylation / myristoyl-CoA / cancer / co/post-translational modification

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