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Structure paper

TitleA Hexamer of a Peptide Derived from A beta 16-36.
Journal, issue, pagesBiochemistry, Vol. 56, Page 6061-6071, Year 2017
Publish dateJun 11, 2017 (structure data deposition date)
AuthorsKreutzer, A.G. / Spencer, R.K. / McKnelly, K.J. / Yoo, S. / Hamza, I.L. / Salveson, P.J. / Nowick, J.S.
External linksBiochemistry / PubMed:29028351
MethodsX-ray diffraction
Resolution1.718 - 2.08 Å
Structure data

PDB-5w4h:
X-ray crystallographic structure of a beta-hairpin peptide mimic derived from Abeta 16-36. Synchrotron data set. (ORN)KLV(MEA)FAE(ORN)AIIGLMV.
Method: X-RAY DIFFRACTION / Resolution: 1.718 Å

PDB-5w4i:
X-ray crystallographic structure of a beta-hairpin peptide mimic derived from Abeta 16-36. Rigaku data set. (ORN)KLV(MEA)FAE(ORN)AIIGLMV.
Method: X-RAY DIFFRACTION / Resolution: 2.026 Å

PDB-5w4j:
X-ray crystallographic structure of a beta-hairpin peptide mimic. (ORN)KLV(MEA)FAE(ORN)AIIGLMV.
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-IOD:
IODIDE ION

Source
  • homo sapiens (human)
KeywordsDE NOVO PROTEIN / amyloid / oligomer / Alzheimer's / trimer / PROTEIN FIBRIL

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