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TitleImportance of Scaffold Flexibility/Rigidity in the Design and Directed Evolution of Artificial Metallo-beta-lactamases.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 139, Page 16772-16779, Year 2017
Publish dateJul 12, 2017 (structure data deposition date)
AuthorsSong, W.J. / Yu, J. / Tezcan, F.A.
External linksJ. Am. Chem. Soc. / PubMed:28992705
MethodsX-ray diffraction
Resolution1.98 - 2.65 Å
Structure data

PDB-5xzi:
Crystal structure of the Zn-directed tetramer of the engineered cyt cb562 variant, AB5
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-5xzj:
Crystal structure of the Zn-directed tetramer of the engineered cyt cb562 variant, C96T/AB5
Method: X-RAY DIFFRACTION / Resolution: 1.98 Å

Chemicals

ChemComp-HEC:
HEME C

ChemComp-ZN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsELECTRON TRANSPORT / de novo protein

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