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TitleRemarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies
Journal, issue, pagesOncotarget, Vol. 8, Page 67129-67139, Year 2017
Publish dateApr 29, 2017 (structure data deposition date)
AuthorsHe, M. / Chai, Y. / Qi, J. / Zhang, C.W.H. / Tong, Z. / Shi, Y. / Yan, J. / Tan, S. / Gao, G.F.
External linksOncotarget / PubMed:28978021
MethodsX-ray diffraction
Resolution3.2 Å
Structure data

PDB-5xj3:
Complex structure of ipilimumab-scFv and CTLA-4
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / ipilimumab / CTLA-4 / complex structure

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