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TitleSPA70 is a potent antagonist of human pregnane X receptor.
Journal, issue, pagesNat Commun, Vol. 8, Page 741-741, Year 2017
Publish dateJan 23, 2017 (structure data deposition date)
AuthorsLin, W. / Wang, Y.M. / Chai, S.C. / Lv, L. / Zheng, J. / Wu, J. / Zhang, Q. / Wang, Y.D. / Griffin, P.R. / Chen, T.
External linksNat Commun / PubMed:28963450
MethodsX-ray diffraction
Resolution2.665 Å
Structure data

PDB-5x0r:
Crystal Structure of PXR LBD Complexed with SJB7
Method: X-RAY DIFFRACTION / Resolution: 2.665 Å

Chemicals

ChemComp-4WH:
4-[(4-tert-butylphenyl)sulfonyl]-1-(2,4-dimethoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION

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