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TitleCovalent Lectin Inhibition and Application in Bacterial Biofilm Imaging.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 56, Page 16559-16564, Year 2017
Publish dateNov 28, 2016 (structure data deposition date)
AuthorsWagner, S. / Hauck, D. / Hoffmann, M. / Sommer, R. / Joachim, I. / Muller, R. / Imberty, A. / Varrot, A. / Titz, A.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:28960731
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-5mih:
Crystal structure of the lectin LecA from Pseudomonas aeruginosa in complex with a phenyl-epoxy-galactopyranoside
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-7NU:
phenyl 6,7-anhydro-D-glycero-beta-D-galacto-heptopyranoside

ChemComp-ETE:
2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL

ChemComp-HOH:
WATER

Source
  • pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1) (bacteria)
KeywordsSUGAR BINDING PROTEIN / LECTIN / GALACTOSE BINDING PROTEIN / covalent lectin inhibition

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