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-Structure paper
Title | GRL-09510, a Unique P2-Crown-Tetrahydrofuranylurethane -Containing HIV-1 Protease Inhibitor, Maintains Its Favorable Antiviral Activity against Highly-Drug-Resistant HIV-1 Variants in vitro. |
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Journal, issue, pages | Sci Rep, Vol. 7, Page 12235-12235, Year 2017 |
Publish date | Mar 11, 2017 (structure data deposition date) |
Authors | Amano, M. / Miguel Salcedo-Gomez, P. / Yedidi, R.S. / Delino, N.S. / Nakata, H. / Venkateswara Rao, K. / Ghosh, A.K. / Mitsuya, H. |
External links | Sci Rep / PubMed:28947797 |
Methods | X-ray diffraction |
Resolution | 1.9 Å |
Structure data | PDB-5v4y: |
Chemicals | ChemComp-8FM: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / GRL-09510 / HIV-1 PROTEASE / PROTEASE-INHIBITOR / Pyran / Furan / NONPEPTIDIC / HYDROLASE-HYDROLASE INHIBITOR COMPLEX / CROWN-THF |