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TitleGermline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Journal, issue, pagesNat. Immunol., Vol. 18, Page 1228-1237, Year 2017
Publish dateJul 23, 2017 (structure data deposition date)
AuthorsCulshaw, A. / Ladell, K. / Gras, S. / McLaren, J.E. / Miners, K.L. / Farenc, C. / van den Heuvel, H. / Gostick, E. / Dejnirattisai, W. / Wangteeraprasert, A. ...Culshaw, A. / Ladell, K. / Gras, S. / McLaren, J.E. / Miners, K.L. / Farenc, C. / van den Heuvel, H. / Gostick, E. / Dejnirattisai, W. / Wangteeraprasert, A. / Duangchinda, T. / Chotiyarnwong, P. / Limpitikul, W. / Vasanawathana, S. / Malasit, P. / Dong, T. / Rossjohn, J. / Mongkolsapaya, J. / Price, D.A. / Screaton, G.R.
External linksNat. Immunol. / PubMed:28945243
MethodsX-ray diffraction
Resolution2.85 - 3.2 Å
Structure data

PDB-5wjl:
Crystal Structure of HLA-A*11:01 with GTS1 peptide
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-5wjn:
Crystal Structure of HLA-A*11:01-GTS3
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-5wkf:
D30 TCR in complex with HLA-A*11:01-GTS1
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

PDB-5wkh:
D30 TCR in complex with HLA-A*11:01-GTS3
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-K:
Unknown entry

Source
  • homo sapiens (human)
  • dengue virus 1
  • dengue virus 3
KeywordsIMMUNE SYSTEM / HLA / TCR / dengue / CD8 T cells

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