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Structure paper

TitleA homodimer interface without base pairs in an RNA mimic of red fluorescent protein.
Journal, issue, pagesNat. Chem. Biol., Vol. 13, Page 1195-1201, Year 2017
Publish dateAug 21, 2016 (structure data deposition date)
AuthorsWarner, K.D. / Sjekloca, L. / Song, W. / Filonov, G.S. / Jaffrey, S.R. / Ferre-D'Amare, A.R.
External linksNat. Chem. Biol. / PubMed:28945234
MethodsX-ray diffraction
Resolution2.35 - 2.51 Å
Structure data

PDB-5bjo:
Crystal structure of the Corn RNA aptamer in complex with DFHO, site-specific 5-iodo-U
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-5bjp:
Crystal structure of the Corn RNA aptamer in complex with DFHO, iridium hexammine soak
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-747:
(5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one

ChemComp-HOH:
WATER

ChemComp-IR:
Unknown entry

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

Source
  • synthetic construct (others)
KeywordsRNA / aptamer / fluorogenic RNA

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