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TitleA reductive aminase from Aspergillus oryzae.
Journal, issue, pagesNat Chem, Vol. 9, Page 961-969, Year 2017
Publish dateJun 23, 2016 (structure data deposition date)
AuthorsAleku, G.A. / France, S.P. / Man, H. / Mangas-Sanchez, J. / Montgomery, S.L. / Sharma, M. / Leipold, F. / Hussain, S. / Grogan, G. / Turner, N.J.
External linksNat Chem / PubMed:28937665
MethodsX-ray diffraction
Resolution1.82 - 2.35 Å
Structure data

PDB-5g6r:
Imine reductase from Aspergillus oryzae
Method: X-RAY DIFFRACTION / Resolution: 1.82 Å

PDB-5g6s:
Imine reductase from Aspergillus oryzae in complex with NADP(H) and (R)-rasagiline
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-HOH:
WATER

ChemComp-RAU:
RASAGILINE / medication*YM

Source
  • aspergillus oryzae (mold)
KeywordsOXIDOREDUCTASE / IMINE REDUCTASE / NADPH / AMINE

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