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TitleTrispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques.
Journal, issue, pagesScience, Vol. 358, Page 85-90, Year 2017
Publish dateJul 18, 2017 (structure data deposition date)
AuthorsXu, L. / Pegu, A. / Rao, E. / Doria-Rose, N. / Beninga, J. / McKee, K. / Lord, D.M. / Wei, R.R. / Deng, G. / Louder, M. ...Xu, L. / Pegu, A. / Rao, E. / Doria-Rose, N. / Beninga, J. / McKee, K. / Lord, D.M. / Wei, R.R. / Deng, G. / Louder, M. / Schmidt, S.D. / Mankoff, Z. / Wu, L. / Asokan, M. / Beil, C. / Lange, C. / Leuschner, W.D. / Kruip, J. / Sendak, R. / Do Kwon, Y. / Zhou, T. / Chen, X. / Bailer, R.T. / Wang, K. / Choe, M. / Tartaglia, L.J. / Barouch, D.H. / O'Dell, S. / Todd, J.P. / Burton, D.R. / Roederer, M. / Connors, M. / Koup, R.A. / Kwong, P.D. / Yang, Z.Y. / Mascola, J.R. / Nabel, G.J.
External linksScience / PubMed:28931639
MethodsX-ray diffraction
Resolution3.549 Å
Structure data

PDB-5whz:
PGDM1400-10E8v4 CODV Fab
Method: X-RAY DIFFRACTION / Resolution: 3.549 Å

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / cross-over dual variable immunoglobin / multifunctional biotherapeutic format / bispecific property / CODV / HIV

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