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TitleStructural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase.
Journal, issue, pagesBiochemistry, Vol. 56, Page 5274-5277, Year 2017
Publish dateFeb 24, 2017 (structure data deposition date)
AuthorsLichman, B.R. / Sula, A. / Pesnot, T. / Hailes, H.C. / Ward, J.M. / Keep, N.H.
External linksBiochemistry / PubMed:28915025
MethodsX-ray diffraction
Resolution1.85 - 2 Å
Structure data

PDB-5n8q:
Structure of truncated Norcoclaurine Synthase from Thalictrum flavum
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-5non:
Structure of truncated Norcoclaurine Synthase from Thalictrum flavum with product mimic
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-93H:
4-[2-[2-(4-methoxyphenyl)ethylamino]ethyl]benzene-1,2-diol

Source
  • thalictrum flavum subsp. glaucum (plant)
KeywordsLYASE / Pictet Spengler condensation / Dopamine

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