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TitleStabilizing an amyloidogenic lambda 6 light chain variable domain.
Journal, issue, pagesFEBS J., Vol. 284, Page 3702-3717, Year 2017
Publish dateMar 11, 2016 (structure data deposition date)
AuthorsLuna-Martinez, O.D. / Hernandez-Santoyo, A. / Villalba-Velazquez, M.I. / Sanchez-Alcala, R. / Fernandez-Velasco, D.A. / Becerril, B.
External linksFEBS J. / PubMed:28898537
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-5ir3:
Crystal structure of the recombinant highest fibrillogenic natural mutant (obtained from patient AR) derived from lambda 6 light chain variable domain
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / BETA-SANDWICH / IMMUNOGLOBULIN / AL AMYLOIDOSIS

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