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Structure paper

TitleA rational approach to enhancing antibody Fc homodimer formation for robust production of antibody mixture in a single cell line
Journal, issue, pagesJ. Biol. Chem., Vol. 292, Page 17885-17896, Year 2017
Publish dateAug 7, 2017 (structure data deposition date)
AuthorsYu, J. / Wang, X. / Xu, T. / Jin, Q. / Duan, J. / Wu, J. / Wu, H. / Ye, S.
External linksJ. Biol. Chem. / PubMed:28878018
MethodsX-ray diffraction
Resolution2.653 Å
Structure data

PDB-5y56:
Fc mutant (K392D/K409D/D399K)
Method: X-RAY DIFFRACTION / Resolution: 2.653 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / IgG Fc / homodimer / triple mutantion (K392D/K409D/D399K)

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