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| Title | Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo. |
|---|---|
| Journal, issue, pages | J. Exp. Med., Vol. 214, Page 2573-2590, Year 2017 |
| Publish date | Jun 16, 2017 (structure data deposition date) |
Authors | Medina-Ramirez, M. / Garces, F. / Escolano, A. / Skog, P. / de Taeye, S.W. / Del Moral-Sanchez, I. / McGuire, A.T. / Yasmeen, A. / Behrens, A.J. / Ozorowski, G. ...Medina-Ramirez, M. / Garces, F. / Escolano, A. / Skog, P. / de Taeye, S.W. / Del Moral-Sanchez, I. / McGuire, A.T. / Yasmeen, A. / Behrens, A.J. / Ozorowski, G. / van den Kerkhof, T.L.G.M. / Freund, N.T. / Dosenovic, P. / Hua, Y. / Gitlin, A.D. / Cupo, A. / van der Woude, P. / Golabek, M. / Sliepen, K. / Blane, T. / Kootstra, N. / van Breemen, M.J. / Pritchard, L.K. / Stanfield, R.L. / Crispin, M. / Ward, A.B. / Stamatatos, L. / Klasse, P.J. / Moore, J.P. / Nemazee, D. / Nussenzweig, M.C. / Wilson, I.A. / Sanders, R.W. |
External links | J. Exp. Med. / PubMed:28847869 |
| Methods | X-ray diffraction |
| Resolution | 3.202 Å |
| Structure data | ![]() PDB-5w6d: |
| Chemicals | ![]() ChemComp-NAG: |
| Source |
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Keywords | VIRAL PROTEIN/Immune System / HIV-1 broadly neutralizing antibody / VIRAL PROTEIN-Immune System complex |
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human immunodeficiency virus 1
homo sapiens (human)
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