+Search query
-Structure paper
Title | Design and Optimization of Benzopiperazines as Potent Inhibitors of BET Bromodomains. |
---|---|
Journal, issue, pages | ACS Med Chem Lett, Vol. 8, Page 847-852, Year 2017 |
Publish date | May 3, 2017 (structure data deposition date) |
![]() | Millan, D.S. / Kayser-Bricker, K.J. / Martin, M.W. / Talbot, A.C. / Schiller, S.E.R. / Herbertz, T. / Williams, G.L. / Luke, G.P. / Hubbs, S. / Alvarez Morales, M.A. ...Millan, D.S. / Kayser-Bricker, K.J. / Martin, M.W. / Talbot, A.C. / Schiller, S.E.R. / Herbertz, T. / Williams, G.L. / Luke, G.P. / Hubbs, S. / Alvarez Morales, M.A. / Cardillo, D. / Troccolo, P. / Mendes, R.L. / McKinnon, C. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.67 Å |
Structure data | ![]() PDB-5vom: |
Chemicals | ![]() ChemComp-9GY: ![]() ChemComp-HOH: |
Source |
|
![]() | Transcription/Inhibitor / bromodomain Brd4 BET Benzopiperazine / Transcription-Inhibitor complex |