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-Structure paper
Title | The Mechanism of Regulation of Pantothenate Biosynthesis by the PanD-PanZAcCoA Complex Reveals an Additional Mode of Action for the Antimetabolite N-Pentyl Pantothenamide (N5-Pan). |
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Journal, issue, pages | Biochemistry, Vol. 56, Page 4931-4939, Year 2017 |
Publish date | Aug 22, 2016 (structure data deposition date) |
Authors | Arnott, Z.L.P. / Nozaki, S. / Monteiro, D.C.F. / Morgan, H.E. / Pearson, A.R. / Niki, H. / Webb, M.E. |
External links | Biochemistry / PubMed:28832133 |
Methods | X-ray diffraction |
Resolution | 1.16 Å |
Structure data | PDB-5ls7: |
Chemicals | ChemComp-GOL: ChemComp-PEG: ChemComp-ACO: ChemComp-MG: ChemComp-CO2: ChemComp-SCN: ChemComp-74C: ChemComp-HOH: |
Source |
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Keywords | LYASE / protein derived cofactor / coenzyme A biosynthesis / protein complex / metabolic pathway regulation |