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TitleSelection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers.
Journal, issue, pagesSci Rep, Vol. 7, Page 8390-8390, Year 2017
Publish dateDec 7, 2016 (structure data deposition date)
AuthorsKoch, K. / Kalusche, S. / Torres, J.L. / Stanfield, R.L. / Danquah, W. / Khazanehdari, K. / von Briesen, H. / Geertsma, E.R. / Wilson, I.A. / Wernery, U. ...Koch, K. / Kalusche, S. / Torres, J.L. / Stanfield, R.L. / Danquah, W. / Khazanehdari, K. / von Briesen, H. / Geertsma, E.R. / Wilson, I.A. / Wernery, U. / Koch-Nolte, F. / Ward, A.B. / Dietrich, U.
External linksSci Rep / PubMed:28827559
MethodsX-ray diffraction
Resolution1.153 - 2.3 Å
Structure data

PDB-5u64:
Camel nanobody VHH-28
Method: X-RAY DIFFRACTION / Resolution: 1.153 Å

PDB-5u65:
Camel Nanobody VHH-5
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • camelus dromedarius (Arabian camel)
KeywordsIMMUNE SYSTEM / neutralizing antibody / camel vhh nanobody / HIV-1 / nanobody VHH

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