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Title | Selective Targeting by a Mechanism-Based Inactivator against Pyridoxal 5'-Phosphate-Dependent Enzymes: Mechanisms of Inactivation and Alternative Turnover. |
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Journal, issue, pages | Biochemistry, Vol. 56, Page 4951-4961, Year 2017 |
Publish date | May 22, 2017 (structure data deposition date) |
![]() | Mascarenhas, R. / Le, H.V. / Clevenger, K.D. / Lehrer, H.J. / Ringe, D. / Kelleher, N.L. / Silverman, R.B. / Liu, D. |
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Methods | X-ray diffraction |
Resolution | 1.72 - 1.8 Å |
Structure data | ![]() PDB-5vwo: ![]() PDB-5vwq: ![]() PDB-5vwr: |
Chemicals | ![]() ChemComp-9QJ: ![]() ChemComp-HOH: ![]() ChemComp-PMP: ![]() ChemComp-PL6: ![]() ChemComp-GOL: |
Source |
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![]() | TRANSFERASE / Aminotransferase / Mechanism-based inactivator / PLP / Aspartate aminotransferase / PMP / (1R / 3S / 4S)-3-amino-4-fluorocyclopentane-1-carboxylic acid (FCP) / ketimine / alpha-ketoglutarate |