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-Structure paper
Title | Synthesis and Evaluation of Asymmetric Acyclic Nucleoside Bisphosphonates as Inhibitors of Plasmodium falciparum and Human Hypoxanthine-Guanine-(Xanthine) Phosphoribosyltransferase. |
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Journal, issue, pages | J. Med. Chem., Vol. 60, Page 7539-7554, Year 2017 |
Publish date | Jun 22, 2017 (structure data deposition date) |
![]() | Spacek, P. / Keough, D.T. / Chavchich, M. / Dracinsky, M. / Janeba, Z. / Naesens, L. / Edstein, M.D. / Guddat, L.W. / Hockova, D. |
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Methods | X-ray diffraction |
Resolution | 2.346 Å |
Structure data | ![]() PDB-5w8v: |
Chemicals | ![]() ChemComp-9YP: ![]() ChemComp-MG: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / 6-oxopurine; phosphoribosyltransferase; hypoxanthine; guanine; nucleoside phosphonate |