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TitleInhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors.
Journal, issue, pagesFuture Med Chem, Vol. 9, Page 1465-1481, Year 2017
Publish dateAug 9, 2016 (structure data deposition date)
AuthorsRondelet, G. / Fleury, L. / Faux, C. / Masson, V. / Dubois, J. / Arimondo, P.B. / Willems, L. / Wouters, J.
External linksFuture Med Chem / PubMed:28795598
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-5lod:
Crystal structure of HhaI DNA methyltransferase in APO form
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • haemophilus parahaemolyticus (bacteria)
KeywordsTRANSFERASE / M.HhaI / C5-METHYLCYTOSINE / APO FORM / DNA methyltransferase

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