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Title2'-Deoxyribosyltransferase from Leishmania mexicana, an efficient biocatalyst for one-pot, one-step synthesis of nucleosides from poorly soluble purine bases.
Journal, issue, pagesAppl. Microbiol. Biotechnol., Vol. 101, Page 7187-7200, Year 2017
Publish dateDec 19, 2018 (structure data deposition date)
AuthorsCrespo, N. / Sanchez-Murcia, P.A. / Gago, F. / Cejudo-Sanches, J. / Galmes, M.A. / Fernandez-Lucas, J. / Mancheno, J.M.
External linksAppl. Microbiol. Biotechnol. / PubMed:28785897
MethodsX-ray diffraction
Resolution1.66 Å
Structure data

PDB-6qai:
2-desoxiribosyltransferase from Leishmania mexicana
Method: X-RAY DIFFRACTION / Resolution: 1.66 Å

Chemicals

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • leishmania mexicana (eukaryote)
KeywordsTRANSFERASE / deoxyribosyltransferase / enzymatic synthesis / oligomeric assembly / purine nucleoside analogues / protein crystallography

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