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TitleHomodimerization attenuates the anti-inflammatory activity of interleukin-37.
Journal, issue, pagesSci Immunol, Vol. 2, Year 2017
Publish dateJan 17, 2016 (structure data deposition date)
AuthorsEllisdon, A.M. / Nold-Petry, C.A. / D'Andrea, L. / Cho, S.X. / Lao, J.C. / Rudloff, I. / Ngo, D. / Lo, C.Y. / Soares da Costa, T.P. / Perugini, M.A. ...Ellisdon, A.M. / Nold-Petry, C.A. / D'Andrea, L. / Cho, S.X. / Lao, J.C. / Rudloff, I. / Ngo, D. / Lo, C.Y. / Soares da Costa, T.P. / Perugini, M.A. / Conroy, P.J. / Whisstock, J.C. / Nold, M.F.
External linksSci Immunol / PubMed:28783685
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-5hn1:
Crystal structure of Interleukin-37
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCYTOKINE / Interleukin-1 Cytokine Inflammation Interleukin-18

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