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Structure paper

TitleStructural basis for potent antibody-mediated neutralization of human cytomegalovirus.
Journal, issue, pagesSci Immunol, Vol. 2, Year 2017
Publish dateMay 2, 2017 (structure data deposition date)
AuthorsChandramouli, S. / Malito, E. / Nguyen, T. / Luisi, K. / Donnarumma, D. / Xing, Y. / Norais, N. / Yu, D. / Carfi, A.
External linksSci Immunol / PubMed:28783665
MethodsX-ray diffraction
Resolution3.02 - 5.9 Å
Structure data

PDB-5vob:
Crystal structure of HCMV Pentamer in complex with neutralizing antibody 8I21
Method: X-RAY DIFFRACTION / Resolution: 3.02 Å

PDB-5voc:
Crystal structure of HCMV Pentamer in complex with neutralizing antibody 8I21 - Low resolution dataset for initial phasing by SAD
Method: X-RAY DIFFRACTION / Resolution: 3.99 Å

PDB-5vod:
Crystal structure of HCMV Pentamer in complex with neutralizing antibody 9I6
Method: X-RAY DIFFRACTION / Resolution: 5.9 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • human cytomegalovirus
  • human cytomegalovirus (strain 5508)
  • human cytomegalovirus (strain ad169)
  • human cytomegalovirus (strain merlin)
  • homo sapiens (human)
KeywordsViral Protein/Immune System / HCMV / neutralizing epitope / immunogen / viral entry / Pentamer / vaccine / Viral Protein-Immune System complex / IMMUNE SYSTEM

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