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TitleT-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein.
Journal, issue, pagesPLoS Pathog., Vol. 13, Page e1006469-e1006469, Year 2017
Publish dateAug 13, 2016 (structure data deposition date)
AuthorsFisher, C.R. / Sutton, H.J. / Kaczmarski, J.A. / McNamara, H.A. / Clifton, B. / Mitchell, J. / Cai, Y. / Dups, J.N. / D'Arcy, N.J. / Singh, M. ...Fisher, C.R. / Sutton, H.J. / Kaczmarski, J.A. / McNamara, H.A. / Clifton, B. / Mitchell, J. / Cai, Y. / Dups, J.N. / D'Arcy, N.J. / Singh, M. / Chuah, A. / Peat, T.S. / Jackson, C.J. / Cockburn, I.A.
External linksPLoS Pathog. / PubMed:28759640
MethodsX-ray diffraction
Resolution2.52 Å
Structure data

PDB-5szf:
2A10 FAB fragment 2.54 Angstoms
Method: X-RAY DIFFRACTION / Resolution: 2.52 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Malaria Antibody

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