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-Structure paper
Title | Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors. |
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Journal, issue, pages | ACS Med Chem Lett, Vol. 8, Page 726-731, Year 2017 |
Publish date | Mar 15, 2017 (structure data deposition date) |
![]() | Lechtenberg, B.C. / Mace, P.D. / Sessions, E.H. / Williamson, R. / Stalder, R. / Wallez, Y. / Roth, G.P. / Riedl, S.J. / Pasquale, E.B. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.2 Å |
Structure data | ![]() PDB-5v60: ![]() PDB-5v61: ![]() PDB-5v62: |
Chemicals | ![]() ChemComp-ACP: ![]() ChemComp-GOL: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-FRZ: ![]() ChemComp-90A: ![]() ChemComp-AKS: |
Source |
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![]() | TRANSFERASE / kinase / MAPK / phosphorylation / cancer / TRANSFERASE/INHIBITOR / TRANSFERASE-TRANSFERASE INHIBITOR complex / TRANSFERASE-INHIBITOR complex |