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Structure paper

TitleBinding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells.
Journal, issue, pagesCell Death Dis, Vol. 8, Page e2950-e2950, Year 2017
Publish dateDec 22, 2016 (structure data deposition date)
AuthorsGenovese, I. / Fiorillo, A. / Ilari, A. / Masciarelli, S. / Fazi, F. / Colotti, G.
External linksCell Death Dis / PubMed:28726784
MethodsX-ray diffraction
Resolution3.74 Å
Structure data

PDB-5mra:
human SCBD (sorcin calcium binding domain) in complex with doxorubicin
Method: X-RAY DIFFRACTION / Resolution: 3.74 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-DM2:
DOXORUBICIN / medication, chemotherapy*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsMETAL BINDING PROTEIN / Sorcin (soluble resistance-related calcium binding protein)

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