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-Structure paper
Title | Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide |
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Journal, issue, pages | Biochem. Biophys. Res. Commun., Vol. 491, Page 416-422, Year 2017 |
Publish date | Jun 28, 2017 (structure data deposition date) |
Authors | Swaminathan, S. / Birudukota, S. / Thakur, M.K. / Parveen, R. / Kandan, S. / Juluri, S. / Shaik, S. / Anand, N.N. / Burri, R.R. / Kristam, R. ...Swaminathan, S. / Birudukota, S. / Thakur, M.K. / Parveen, R. / Kandan, S. / Juluri, S. / Shaik, S. / Anand, N.N. / Burri, R.R. / Kristam, R. / Hallur, M.S. / Rajagopal, S. / Schreuder, H. / Langer, T. / Rudolph, C. / Ruf, S. / Dhakshinamoorthy, S. / Gosu, R. / Kannt, A. |
External links | Biochem. Biophys. Res. Commun. / PubMed:28720493 |
Methods | X-ray diffraction |
Resolution | 1.88 - 2.29 Å |
Structure data | PDB-5xvk: PDB-5xvq: |
Chemicals | ChemComp-SAH: ChemComp-8GC: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / NNMT / MNA / ternary complex / feedback inhibition / T2D |