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-Structure paper
Title | Modulation of nongenomic activation of PI3K signalling by tetramerization of N-terminally-cleaved RXR alpha. |
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Journal, issue, pages | Nat Commun, Vol. 8, Page 16066-16066, Year 2017 |
Publish date | Sep 12, 2016 (structure data deposition date) |
Authors | Chen, L. / Aleshin, A.E. / Alitongbieke, G. / Zhou, Y. / Zhang, X. / Ye, X. / Hu, M. / Ren, G. / Chen, Z. / Ma, Y. ...Chen, L. / Aleshin, A.E. / Alitongbieke, G. / Zhou, Y. / Zhang, X. / Ye, X. / Hu, M. / Ren, G. / Chen, Z. / Ma, Y. / Zhang, D. / Liu, S. / Gao, W. / Cai, L. / Wu, L. / Zeng, Z. / Jiang, F. / Liu, J. / Zhou, H. / Cadwell, G. / Liddington, R.C. / Su, Y. / Zhang, X.K. |
External links | Nat Commun / PubMed:28714476 |
Methods | X-ray diffraction |
Resolution | 2.6 Å |
Structure data | PDB-5tbp: |
Chemicals | ChemComp-7A4: ChemComp-ACT: ChemComp-DMS: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | TRANSCRIPTION / nuclear receptor / Sulindac / AKT activation / Complex / tetramer / RXR / LBD |